Anti-YBX1 antibody

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.

• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Applications: WB,IHC
• Reactivity: Human,Mouse,Rat
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purification: Affinity purification
• Clone: NA
• Concentration: NA
• Gene: YBX1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human YBX1 (NP_004550.2).