PROTAC HK2 Degrader-1
PROTAC HK2 Degrader-1
2092.30 EUR
Categoria di prodotto: Commercio e industria > Scienza e laboratorio
Fornitore: Gentaur Taglia: 1 mg
Prodotti relativi
PROTAC BET Degrader-1
PROTAC RAR Degrader-1
PROTAC TG2 degrader-1
PROTAC BET Degrader-1
PROTAC BET Degrader-1
PROTAC HK2 Degrader-1 is a PROTAC consisting of Lonidamine (HY-B0486) as a target protein Hexokinase 2 (HK2) inhibitor and Thalidomide (HY-14658) as a CRBN ligand-linked PROTAC. PROTAC HK2 Degrader-1 selectively inhibits the proliferation of breast cancer cells by forming a ternary complex through the ubiquitin-proteasome system to degrade Hexokinase 2 (HK2) protein leading to mitochondrial damage and cell death. PROTAC HK2 Degrader-1 effectively inhibits breast tumor growth and reduces the colonic side effects of cisplatin for breast cancer research[1].
- -20°C, 3 years
- 4°C, 2 years (Powder)
- Purity: 98.66
- Formula: C32H28Cl2N6O5
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- SMILES: O=C(N1)CCC(N(C(C2=C3C=CC=C2NCCCCNC(C4=NN(C5=C4C=CC=C5)CC6=C(C=C(C=C6)Cl)Cl)=O)=O)C3=O)C1=O
- Molecular Weight: 647.51
- Applications: Cancer-Kinase/protease
For research use only. Not to be used for human or animal treatment or consumption.
Aggiungi una recensione
0 recensione per PROTAC HK2 Degrader-1