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PROTAC BTK Degrader-1
0.01 EUR
Categoria di prodotto: Commercio e industria > Scienza e laboratorio
Catalog number: / Dimensione: / Prezzo: EUR (IVA esclusa)
Categoria di prodotto: Commercio e industria > Scienza e laboratorio
MedChemExpress
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PROTAC BTK Degrader-1 is a potent, selective and orally active PROTAC BTK degrader with an IC50 value of 34.51 nM and 64.56 nM for BTK WT and BTK-481S, respectively. PROTAC BTK Degrader-1 effectively reduces BTK protein levels and suppresses tumor growth[1]. PROTAC BTK Degrader-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- CAS number: 2801715-13-7
- Formula: C43H43N9O4
- Solubility: 10 mM in DMSO
- SMILES: O=C(N1)C(CCC1=O)N(C2=O)CC3=C2C=CC(C#CCN4CCC(CC4)N5CCC(CC5)N6N=C(C7=C(N=CN=C76)N)C8=CC=C(C=C8)OC9=CC=CC=C9)=C3
- Molecular Weight: 749.86
- Applications: Cancer-Kinase/protease
For research use only. Not to be used for human or animal treatment or consumption.
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