IMP-1700
IMP-1700
0.01 EUR
Categoria di prodotto: Commercio e industria > Scienza e laboratorio
Fornitore: Gentaur Taglia: 1g
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- SMILES: O=C(O)C1=CN(C2=CC(=C(F)C=C2C1=O)N3CCN(C(=S)NC4=CC=C(C=C4)C(F)(F)F)CC3)C5CC5
- Formula: C25H22F4N4O3S
- Purity: 0.98
- CAS#: 1458674-25-3
- Molecular Weight: 534.53
- Bioactivity: IMP-1700 is an inhibitor of bacterial DNA repair.1It potentiates the activity of the quinolone antibiotic ciprofloxacin against methicillin-resistantS. aureus(MRSA) with a combination index value of 0.7. IMP-1700 inhibits the ciprofloxacin-induced bacterial SOS response, a process that repairs DNA damage, in a reporter assay in a concentration-dependent manner. It is also active againstE. coli, as well as methicillin-resistant and -sensitive S. aureus, when used alone (EC50s = 0.5, 0.21, and 3.8 μM, respectively).
For research use only.
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