Ganglioside GQ1b Mixture (sodium salt)
Ganglioside GQ1b Mixture (sodium salt)
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Categoria di prodotto: Commercio e industria > Scienza e laboratorio
Fornitore: Gentaur Taglia: 10mg
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Ganglioside GQ1b Mixture (sodium salt)
- SMILES: CCCCCCCCCCCCC/C=C/[C@]([H])([C@](NC(CCCCCCCCCCCCCCCCC)=O)([H])CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O[C@@]3(C([O-])=O)O[C@H]([C@@H]([C@H](C3)O)NC(C)=O)[C@@H](O)[C@H](O[C@@]4(C([O-])=O)O[C@H]([C@@H]([C@H](C4)O)N
- Formula: C106H178N6O55?4Na (for Sphingosine C18:1)
- Purity: 0.98
- CAS#: 68652-37-9
- Molecular Weight: 2508.5
- Bioactivity: Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when used at a concentration of 5 nM. Ganglioside GQ1b promotes differentiation of murine embryonic stem cells (mESCs) to neuronal precursor and glial cells via activation of the ERK1/2 pathway. It also induces differentiation of murine keratinocytes through phosphoinositide turnover. Ganglioside GQ1b mixture contains ganglioside GQ1b molecular species with C18:1 and C20:1 sphingoid backbones.
For research use only.
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