Anti-SPHK1 antibody
Prodotti relativi
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Clonality: Polyclonal
- Host: Rabbit
- Conjugation: Unconjugated
- Applications: WB,IF
- Reactivity: Human,Mouse
- Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Purification: Affinity purification
- Clone: NA
- Concentration: NA
- Gene: SPHK1
- Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-384 of human SPHK1 (NP_001136074.1).
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