Anti-IL5 antibody

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2. This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Applications: WB,IHC
• Reactivity: Human,Mouse,Rat
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purification: Affinity purification
• Clone: NA
• Concentration: NA
• Gene: IL5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-134 of human IL5 (NP_000870.1).