Anti-GLE1 antibody
Prodotti relativi
This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Clonality: Polyclonal
- Host: Rabbit
- Conjugation: Unconjugated
- Applications: WB
- Reactivity: Mouse,Rat
- Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Purification: Affinity purification
- Clone: NA
- Concentration: NA
- Gene: GLE1
- Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GLE1 (NP_001003722.1).
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