SARS-CoV-2 (COVID-19) Spike S1 Recombinant Protein

The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses as well as protective immunity.

Store the lyophilized protein at -20°C to -20°C for long term. After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week

• Tested Applications: E, WB
• Applications: This recombinant protein can be used for WB, ELISA. For research use only.
• Predicted Molecular Weight: 75.8 kDa
• Physical state: Lyophilized
• Buffer: PBS, pH 7.4
• Concentration: N/A
• NCBI official symbol: S
• Accession #: YP_009724390.1
• Protein GI: N/A
• NCBI gene ID#: 43740568
• NCBI official full name: surface glycoprotein
• NCBI organism: Severe acute respiratory syndrome coronavirus 2
• Peptide sequence: Val16-Arg685
• SWISSPROT #: P0DTC2
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: HEK293 cells
• Species: SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein
• By Source: Human Cells
• By Species: Other
• Fusion tag: His tag at C-terminus
• Sequence: Val16-Arg685
• Biology activity: Measured by its binding ability in a functional ELISA.Immobilized Recombinant Human ACE2 at 2 g/mL (100L/well ) can bind Recombinant nCoV-S1, The EC50 of nCoV-S1 is 0.25-0.45 µg/mL
• Purity: > 90% as determined by SDS-PAGE
• >
• 95% by HPLC.

Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.