G-CSF Recombinant Protein
Prodotti relativi
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
The lyophilized G-CSF recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted G-CSF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing G-CSF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Tested Applications: N/A
- Applications: N/A
- Predicted Molecular Weight: N/A
- Physical state: Lyophilized
- Buffer: N/A
- Concentration: N/A
- NCBI official symbol: CSF3
- Accession #: P09919
- Protein GI: 743523204
- NCBI gene ID#: 1440
- NCBI official full name: colony stimulating factor 3
- NCBI organism: Homo sapiens
- Peptide sequence: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
- SWISSPROT #: P09919-2
- Background Reference 1: N/A
- Background Reference 2: N/A
- Background Reference 3: N/A
- Background Reference 4: N/A
- Background Reference 5: N/A
- Source: E. coli
- Species: Human
- By Source: E. Coli
- By Species: Human
- Fusion tag: N/A
- Sequence: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
- Biology activity: The ED50 was determined by the dose - dependent stimulation of the proliferation of murine M - NFS - 60 cells is &le
- 0.1 ng/mL, corresponding to a specific activity of &ge
- 1 x 107 units/mg.
- Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Endotoxin level is less than 0.1 ng per µg (1EU/µg).
This product is for research use only.
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