Recombinant Human IL-17 (IL-17A) Protein

The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules.  Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles.  The six known members of this family, IL-17A through IL-17F, are secreted as homodimers.  IL-17A exhibits cross-species bioactivity between human and murine cells.  Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains.

Store in -20°c for long term storage. After reconstitution, store in 4°c for short term usage within a few days. Avoid freeze-thaw cycles.

• category: Recombinant Proteins
• gene name: IL17A
• contents: Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
• uniprot_id: Q16552
• form: Solid
• white powder or thin/invisible film
• purification: NA
• applications: Cell Culture
• subcellular_localization: Secreted.
• source: E. Coli

this product is available in other size, Various Sizes, please contact us for more information.