Phospho-PRKCG (Thr655) Antibody
Phospho-PRKCG (Thr655) Antibody
PRKCG (Phospho-Thr655) Antibody detects endogenous levels of PRKCG only when phosphorylated at Thr655.
- Additional Information
Questo prodotto non ha una descrizione dettagliata. Contattaci per i dettagli su questo prodotto.
- Antigen: Phospho-PRKCG (Thr655)
- Reactivity: Human,Mouse,Rat
- Host: Rabbit
- Clonality: Polyclonal
- Isotype: IgG
- Application: WB,ELISA
- ImmunogenA synthesized peptide derived from human PRKCG (Phospho-Thr655).
- purificationThe antibody is from purified?rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
PRKCG (Phospho- Thr655) Antibody
Phospho-PRKCG (Thr655) Blocking Peptide
Antibody for Human PRKCGA polyclonal antibody for PRKCG from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human PRKCG (aa. 150-250). The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This PRKCG antibody is conjugated to Dylight 488.SPC-782D-DY488
Antibody for Human PRKCGA polyclonal antibody for PRKCG from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human PRKCG (aa. 150-250). The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This PRKCG antibody is conjugated to Dylight 594.SPC-782D-DY594
PRKCG ELISA Kit (Rat) (OKEH05969)Description of target: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing plasma membrane-associated GRIA4 expression. In primary cerebellar neurons treated with the agonist 3,5-dihyidroxyphenylglycine, functions downstream of the metabotropic glutamate receptor GRM5/MGLUR5 and phosphorylates GRIN1/NMDAR1 receptor which plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. May be involved in the regulation of hippocampal long-term potentiation (LTP), but may be not necessary for the process of synaptic plasticity. May be involved in desensitization of mu-type opioid receptor-mediated G-protein activation in the spinal cord, and may be critical for the development and/or maintenance of morphine-induced reinforcing effects in the limbic forebrain. May modulate the functionality of mu-type-opioid receptors by participating in a signaling pathway which leads to the phosphorylation and degradation of opioid receptors. May also contributes to chronic morphine-induced changes in nociceptive processing. Plays a role in neuropathic pain mechanisms and contributes to the maintenance of the allodynia pain produced by peripheral inflammation. Plays an important role in initial sensitivity and tolerance to ethanol, by mediating the behavioral effects of ethanol as well as the effects of this drug on the GABA(A) receptors. During and after cerebral ischemia modulate neurotransmission and cell survival in synaptic membranes, and is involved in insulin-induced inhibition of necrosis, an important mechanism for minimizing ischemic injury. Required for the elimination of multiple climbing fibers during innervation of Purkinje cells in developing cerebellum. Is activated in lens epithelial cells upon hydrogen peroxide treatment, and phosphorylates connexin-43 (GJA1/CX43), resulting in disassembly of GJA1 gap junction plaques and inhibition of gap junction activity which could provide a protective effect against oxidative stress. Phosphorylates p53/TP53 and promotes p53/TP53-dependent apoptosis in response to DNA damage. Involved in the phase resetting of the cerebral cortex circadian clock during temporally restricted feeding. Stabilizes the core clock component ARNTL/BMAL1 by interfering with its ubiquitination, thus suppressing its degradation, resulting in phase resetting of the cerebral cortex clock.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mLOKEH05969
Metodo: ELISA Principio: Il reagente di rilevamento è realizzato con una tecnologia immunosoppressiva con anticorpi neutralizzanti. Il kit contiene il dominio di legame del recettore 2019-nCoV ricombinante marcato con perossidasi di rafano (RBD-HRP) e il recettore della cellula ospite ACE2 immobilizzato su piastra ELISA. Per informazioni scrivere a: [email protected] Manipolazione dei campioni Campioni: siero o [...]
Metodo: Immunocromatografia a Fluorescenza Principio: Il test contiene RBD e ACE2 etichettati fluorescenti, immobilizzati nell'area del test (T) e il corrispondente anticorpo nell'area del controllo qualità (C). Il kit è così composto: Kit anticorpi neutralizzanti Diluzione dei campioni Contagocce per campioni usa e getta. Per informazioni scrivere a [email protected] Fasi operative: Interpretazione dei risultati: [...]
Metodo: Oro Colloidale Principio: il dispositivo contiene oro colloidale etichettato con la proteina Spike di COVID-19 (RBD); con anticorpo umano IgG immobilizzato nell'area G del test; anticorpo anti-topo umano IgM immobilizzato nell'area M del test e il corrispondente anticorpo nell'area di controllo qualità (C). ---> Testare tutti gli anticorpi IgG e IgM che possono legarsi con [...]