Sgcd sgRNA CRISPR Lentivector (Rat) (Target 1)
- Additional Information
- Shipping conditions: Ice Packs
- Storage conditions: -20C
A cloning plasmid for the SGCD gene.
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.